Glucosamine Sulfate (glycolysis associated with an amino acid, glutamine) participates in the production of proteoglycans with a direct effect on the synthesis of mucosal cartilage by chondrocytes. It inhibits the activity of collagenase (an enzyme that degrades collagen). It is an important element in the composition of mucosal cartilage, a substance that is essential in the structure of cartilage. It is present in bones, skin and appendages. It has an anti-inflammatory action, which reduces the functional index, pain and/or edema.
Chondroitin Sulfate (mucopolysaccharide composed of N-acetyl-galactosamine associated with an amino sugar, or glucuronic acid) captures and transports water to proteoglycans. It inhibits hyaluronidase, an enzyme that reduces the viscosity of hyaluronic acids.
Chondroprotective agent, as it maintains osmotic pressure and protects cartilage:
- Enzymes that damage cartilage, such as collagenase and elastase, reduce the activity of glucosamidase, an enzyme that degrades glucosamine. This substance is also present in bones, skin, cornea and arterial membranes.
- From damage by free radicals, including nitrogen monoxide emitted by chondrocytes.
The synergy of these two substances reinforces the activity of hyaluronic acid present in synovial fluid.
Phenolic heterosides, and especially salicylic acid from Meadowsweet (Filipendula ulmaria) have an anti-inflammatory and analgesic action, due to their uric acid elimination properties. Salicylic acid has a recognized antispasmodic action.
Natural Silicon from Bamboo (Bambusa arundinacea) increases joint mobility, promotes the synthesis of new cartilage and intensifies the formation of chondroblasts.
Methylsulfonylmethane (MSM) is a substance that drains organic tissues and eliminates inflammatory symptoms. It forms or restores sulfur bridges. MSM rapidly restores the flexibility and permeability of the cell membrane, regulating osmotic-cellular pressures, thereby suppressing the origin of pain.
Manganese is a cofactor of countless enzymatic reactions associated with chondroformation and chondroabsorption. Manganese increases the effectiveness of glucosamine.




